Desflurane cardiovascular effects are mentioned here. There is a decrease in systemic vascular resistance and peripheral vasodilatation. Cardiac depression, a dose-dependent tachycardia and fall in blood pressure are seen. Along with N20 this effect is minimal. Splanchnic and renal blood flow is preserved. Desflurane is a direct coronary vasodilator. A rapid increase in concentration of […]
The purpose of preoxygenation of a patient before induction of general anesthesia and paralysis is to provide a maximum time that the patient can tolerate apnea. Normal oxygen consumption in a healthy adult is about 250 ml / min desaturations oxygen can occur as quickly as 30-60 seconds in a healthy adult with the FRC
The discovery of anesthesia Inhalation agents heralded the era of modem anesthesia. In 1842, the first general anesthetic administered was recorded by CF Long and W Clarke using diethyl ether; however, they did not publicize it. The first successful public demonstration of anesthesia Inhalation agents was by W.T.G. Morton on 10th October 1846 at the Massachusetts General Hospital Boston,
The anesthesiologist should know that the essential element of an “anesthetic” for an Awake Craniotomy Anesthesia is the surgeon’s local anesthetic technique. Craniotomy is required for removal of space occupying lesions, intracranial vascular pathologies and for drainage of extradural or intradural haematoma. Most important postoperative considerations are regulation of patient’s ICP status, maintenance of cerebral
Laryngeal Mask Airway or LMA was discovered by Archies Brain so also called as a Brain Mask. LMA are special type of airways which are useful in difficult intubation. It is placed blindly in the oropharynx and the cuff is inflated with large volume of air tat is about 30 to 40 ml for a
Isoflurane is a fluorinated methyl ethyl ether. It is an isomer of enflurane. Physical Properties of Isoflurane : • It is Colorless. • It has pungent ethereal odor so induction is not smooth. • Non inflammable, non explosive. • Vapor pressure similar to halothane (240 mmHg). Hence it also has agent specific Isoflurane vaporizer. Anesthetic
The Non Rebreather Masks are the masks that do not allow rebreathing of the gases to take place when a patient is ventilated or he takes spontaneous breaths while the mask is being held. These masks of Non Rebreather type need to have a very high flow of oxygen as most of the oxygen is being lost.
Doxapram injection Doxapram is a specific respiratory stimulant. It stimulates the respiratory center preferentially and has relatively less effect on cortical and spinal sites. Following intravenous doxapram injection the drug stimulates ventilation and increases cardiac output and work. Doxapram dose It is given in a dose of 1-1.5 mg/kg by intravenous injection. Intravenous infusion can also
What is Morphine sulphate Morphine sulphate injection is an opium alkaloid and a standard potent opioid analgesic. This opioid acts as an anxiolytic, hypnotic and sedative. It causes both the stimulation and the depression of the central nervous system. The depression caused by morphine leads to analgesia, respiratory depression, depression of cough reflex and sleep
Sevoflurane metabolic effects are seen when approximately 5% of the dose is metabolized by the liver, catalyzed by cytochrome P450 (2E1) enzyme. While Sevoflurane metabolic effects are studied we see that, it is broken down to hexafluoro isopropanol (HFIP) and fluoride ions. Hexafluoro isopropanol is conjugated with glucuronic acid to form HFIP glucuronide and excreted
