Phenoperidine a new opoid Phenoperidine is chemically related to pethidine and is similar to fentanyl. It is one of the new opioids available now for use in anesthesia for analgesia and as a pre anesthesia medication. Phenoperidine potency One milligram of this new opioid drug is equianalgesic to 100 mg pethidine. Phenoperidine Onset and Duration of […]
The reservoir bag is also called as the Breathing bag. The bag is attached to anesthesia breathing circuits to ventilate the patient. The bag acts as a reservoir for anesthetic gases as well as for oxygen, which when pressed results in the delivery of the gases or oxygen to the patient. An anesthetized and paralyzed
Desflurane mechanism of action is briefly studied. There is a dose-dependent suppression of EEG, at MAC greater than 1.66 the LEG becomes isoelectric. There is no evidence of epileptiform activity. It decreases the amplitude of somatosensory evoked potentials. There is a dose-dependent decrease in cerebral metabolism and cerebral vasodilatation. Cerebral autoregulation is impaired similar to
Pentazocine injection is a synthetic narcotic analgesic derived from benzomorphan. Pentazocine Potency Its analgesic potency of 30 mg is said to be equal to 10 mg of morphine or 75 to 100 mg of pethidine. Pentazocine Dose The usual dose in adults is 20 to 60 mg i.m. (about 1 mg/kg). The oral dose ranges from
What is Buprenorphine injection? Is it an opiod? Buprenorphine is derived from the opium alkaloid thebaine and is closely related to morphine. It has powerful opiod agonist actions as well as partial opiod antagonist actions. It does not seem to cause addiction and physical dependence. Buprenorphine injection Potency It is a potent analgesic, 0.4 mg is equipotent
The anatomy of larynx is extremely important for an anesthesiologist. A through knowledge of the anatomy of larynx is essential for mastering the skill of intubation with a tracheal tube. Larynx is the organ of voice extending from the root of the tongue to trachea and lies opposite C3 to C6 vertebrae. The distance between
All hypnotics drugs act on different subunits of GABA receptors. Gamma amino butyric acid (GABA): This is a major inhibitory amino acid Neuro Transmitter in the brain; its synthesis from glutamate is catalyzed by the enzyme glutamic acid decarboxylase. It binds to either GABA-A or GABA-B receptor following its release from the presynaptic vesicles. GABA-
The history of anesthesia is very old. Anesthesia was used even in the ancient societies of the oldest civilizations wherein opium extracts, alcohol, coca leaves and other plant products were used. Even regional anesthesia in the form of compression on the nerve trunks, application of cold or use of crude local anesthetics was done in
The kinetics of the anaesthetic agents during recovery from inhalant anesthesia are a reversal of the mechanism seen during induction. On cessation of anaesthetic agent, the fall in alveolar concentration is immediate. The gradient between venous blood and alveoli drives the anaesthetic into the alveoli. In terms of recovery from inhalant anesthesia , the poorly
Posterior fossa is a tight infratentorial compartment which harbors vital centers like cerebellum, pons and medulla. Anesthesia for Posterior Fossa Surgery is employed in carious types of space-occupying lesions, i.e., cerebellar tumours, cerebellopontine angle lesions, medulloblastoma, brainstem glioma occur in this area. The patients with posterior fossa tumor presents with features of raised intracranial pressure, brain
