Acute barbiturate poisoning causes depression of the CNS, particularly the respiratory system causing decreased breathing, and the cardiovascular system causing a peripheral circulatory collapse. The frequent and often fatal complications are respiratory (atelectasis, pulmonary edema and bronchopneumonia) or renal (acute renal shutdown). Treatment of acute barbiturate poisoning The severity of barbiturate poisoning is assessed by […]
Diethyl ether anesthetic is the first volatile anesthetic agent used widely for over one-and-a-half centuries. Volatile anesthetic agents like Ether, ethylene, chloroform, trichloroethylene and methoxyflurane are not in use in developed countries. However, ether, trichloroethylene are still in use in some developing countries. Physical properties of Diethyl ether anesthetic : It has a boiling point
Functioning of Isoflurane cerebral blood flow is discussed here. Isoflurane reduces cerebral metabolism and so the oxygen consumption is reduced. At 1 MAC there is a 23% reduction in CMRO2. Isoflurane cerebral blood flow is not associated with seizure activity as opposed to Enflurane. The EEG shows progressive development of slow waves after an initial
Some of the toxicity issues related to desflurane toxicity is that, renal toxicity is not reported even after prolonged exposures and markers of renal function (albuminuria, glucosuria, urinary p-glutathione transferase, serum creatinine and BUN) were not altered after 7 days of exposure to 8 hours MAC of 1.25% desflurane. Desflurane Toxicity might occur at certain
First recognized 50 years ago and used as xenon gas anesthesia in 1957, used for orchidectomy in a 81- year-old. The patient woke up after 2 minutes. Xenon, a by-product of oxygen production during fractional distillation of air. It is said to be a noble gas and is present in air 0.0000087%. Rediscovered in 1990, it
Nitrous oxide induction agent is a weak anaesthetic agent and not suitable as a sole anaesthetic agent. Nitrous oxide induction agent is used to hasten inhalational induction of anaesthesia due to its “concentration and second gas effects”. There is a smooth and pleasant induction. The recovery from anaesthesia is rapid; however, a “diffusion hypoxia”
Ether is still very rarely used in many Developing countries like India. First public demonstration of ether was given by W.T.G. Morton on I6th October 1846 for the removal of jaw tumor. Physical Properties of Ether : • It is pungent smelling liquid decomposes in presence of light, air and heat so stored in amber
Introduction to Laparoscopic Appendicectomy Laparoscopic appendicectomy, a minimally invasive surgical procedure, has gained prominence as an effective treatment for acute appendicitis. This technique involves the use of small incisions and specialized instruments, allowing surgeons to remove the inflamed appendix with reduced trauma to the surrounding tissues. The primary indications for laparoscopic appendicectomy include acute appendicitis,
Anaesthesia for Laparoscopic Appendicectomy: A Comprehensive Guide Read More »
McNarry and Goldhill compared ACDU Scale (Alert, Confused, Drowsy, Unresponsive) and AVPU scale (Alert, responds to Voice, responds to Pain, Unresponsive) by the American college of surgeons with GCS scale for neurological assessment of critically ill ward patients. Just like GCS the ACDS Scale is a method to assess the neurological status and level of
Halothane neuromuscular junction effect produces moderate muscle relaxation, it increases the degree and duration of relaxation produced by nondepolarizing muscle relax- ants. The action is at the postjunctional membrane. There is relaxation of the uterine muscle, which is useful in podalic version procedure but may hinder uterine contraction postpartum. Halothane neuromuscular junction effect may produce
