What is Nitrous oxide gas ? Nitrous oxide gas is a Gaseous Anesthetic agent. Nitrous oxide gas is a colorless, inorganic gas with a sweet taste. The oxygen in the nitrous oxide molecule is not available for tissue respiration as nitrous oxide does not undergo significant decomposition in the body. Nitrous oxide gas, if administered […]
Circulatory system and Enflurane Mechanism Action : Enflurane reduces BP due to vasodilatation as a result of decrease in SVR and cardiac depression. There is increase in heart rate and reduction in cardiac output. It does not sensitize the heart to catecholamines or stimulate the sympathetic nervous system. The margin between adequate anaesthesia and unacceptable hypotension
What is Buprenorphine injection? Is it an opiod? Buprenorphine is derived from the opium alkaloid thebaine and is closely related to morphine. It has powerful opiod agonist actions as well as partial opiod antagonist actions. It does not seem to cause addiction and physical dependence. Buprenorphine injection Potency It is a potent analgesic, 0.4 mg is equipotent
Some of the Sevoflurane respiratory effects include that there is no irritation to the airway, least among inhalation agents, this makes it suitable for inhalational induction, the low blood/gas solubility aids faster induction. Sevoflurane respiratory effects include respiratory depression, reduces minute ventilation, tidal volume and ventilatory response to CO2. Sevoflurane abolishes hypoxic pulmonary vasoconstriction in
Neuroleptic malignant syndrome (NMS) is a clinical syndrome consisting of four primary features: rigidity, altered mental status, hyperthermia, and autonomic instability. It occurs in the setting of the use of dopamine-blocking agents or the withdrawal of dopamine-enhancing medications. Neuroleptic malignant syndrome Epidemiology Incidence of Neuroleptic malignant syndrome is estimated at 0.1% to 2%. There is
Trilene anesthesia is a non-flammable, good analgesic-and cheap agent. Physical properties of trilene anesthesia : It has bp 80°C, VP 60 mm Hg, oil/gas coefficient 600 and blood/gas 12, metabolism 40%, unstable, preservative 1:10,000 thymol as stabilizer and coloured with waxoline blue 1 in 200,000, MAC 0.17%. Trilene anesthesia reacts with sodalime to produce phosgene
When it comes to undergoing a surgical procedure, one of the most important decisions to make is the choice between regional anaesthesia and general anaesthesia. Both options have their advantages and disadvantages, but in this article, we will focus on the benefits of regional anaesthesia over general anaesthesia. What is Regional Anaesthesia? Regional anaesthesia involves
The Benefits of Regional Anaesthesia Compared to General Anaesthesia Read More »
Emergence from anesthesia has cardiorespiratory, metabolic/endocrine and neurologic consequences. Awakening and extubation after anesthesia are associated with haemodynamic arousal lasting 10-25 minutes. This activation is partially mediated by elevations in catecholamine levels and partially by nociceptive stimuli. The aim of emergence after a neurosurgical procedure is to maintain intracerebral and extra-cerebral homeostasis. This implies maintenance
The Poynting effect refers to the phenomenon where mixing of liquid nitrous oxide at low pressure with oxygen at high pressure (in Entonox) leads to formation of gas of nitrous oxide. So oxygen and nitrous oxide both are present in gaseous state in Entonox cylinder. In anesthesia practice the Poynting effect is seen in the
Isoflurane is a fluorinated methyl ethyl ether. It is an isomer of enflurane. Physical Properties of Isoflurane : • It is Colorless. • It has pungent ethereal odor so induction is not smooth. • Non inflammable, non explosive. • Vapor pressure similar to halothane (240 mmHg). Hence it also has agent specific Isoflurane vaporizer. Anesthetic
