Anesthesia

IV Anesthesia

IV Anesthesia or intravenous anesthesia is when anesthesia is given through a vein through injections. Anesthesia is usually started or induced with intravenous or IV anesthesia drugs. The different IV Anesthesia drugs are: Thiopental sodium Midazolam Methohexitone Ketamine Etomidate Propofol Some Steroids Ultra short acting barbiturates The ultra-short acting barbiturates administered as IV Anesthesia to […]

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High Flow oxygen

High Flow oxygen delivery devices are also called as fixed performance devices because their performance is not affected by changes in patient’s tidal volume and respiratory rate and therefore deliver accurate oxygen concentration. High Flow oxygen devices are more effective in treating hypoxemia then low flow systems. Disadvantages of High Flow oxygen devices are: a. Low patient

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Halothane Anesthesia

Halothane Anesthesia is an alkane, halogenated hydrocarbon introduced in 1256. (M Johnston, UK). Physical Properties: Halothane Anesthesia is colorless, sweet smelling, nonirritating, bp 50 degrees C, VP 243 mm Hg, blood/gas 2.5, oil/gas 224, metabolism 20—40%, MAC in 02 ofQ7 /o and 0.29% with N20. It is relat Istable, decopcs on exposure tq.ajr, hence stored

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Desflurane induction

There is rapid desflurane induction of anesthesia because of low solubility in blood, but a mask induction may produce coughing, breath holding, secretions and desaturation. Also the high initial percentage of desflurane induction may cause tachycardia and hypertension due to sympathetic effects. It is not recommended for inhalation induction. Recovery from desflurane induction is faster

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Metabolism of volatile anesthetics

Metabolism of volatile anesthetics is discussed here. Once thought to be chemically inert, inhalation agents, especially the older ones, undergo significant metabolism, bio-transformation and breakdown to potentially toxic intermediates. This process is affected by age, disease, drug interaction and genetics. Inhalation agents are administered in great excess of the amount metabolized unlike other drugs. For

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Malignant hyperthermia

Malignant hyperthermia (MH) is a hypermetabolic disorder of skeletal muscle that is triggered in susceptible individuals by several inhalation anesthetic agents (sevoflurane, desflurane, isoflurane, halothane, enflurane, and methoxyflurane) and succinylcholine. These anesthetic triggers cause intracellular hypercalcemia in skeletal muscle by decreasing the uptake of calcium by the sarcoplasmic reticulum. The intracellular hypercalcemia activates metabolic pathways

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Isoflurane respiratory effects

One of the Isoflurane respiratory effects is that, Isoflurane causes bronchodilatation by inhibiting bronchoconstriction. As with other potent vapours, isoflurane impairs both ventilatory drive and hypoxic pulmonary vasoconstriction leading to hypercapnia and V/Q mismatch. In asthmatic patients due to its lack of arrhythmogenic potential, drugs like aminophylline or agonists such as salbutamol may be less

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Intubation Contraindications

Intubation contraindications can be divided into those Both Nasal and Oral lntubation and those for Nasal Intubation. Both Nasal and Oral lntubation Contraindications • Laryngeal edema. • Epiglottitis. • Laryngotracheobronchitis This is one among the important Intubation Contraindications. In these conditions the airway is already compromised giving very little place for the endotracheal Tube to

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