Acute barbiturate poisoning causes depression of the CNS, particularly the respiratory system causing decreased breathing, and the cardiovascular system causing a peripheral circulatory collapse. The frequent and often fatal complications are respiratory (atelectasis, pulmonary edema and bronchopneumonia) or renal (acute renal shutdown). Treatment of acute barbiturate poisoning The severity of barbiturate poisoning is assessed by
The history of anesthesia is very old. Anesthesia was used even in the ancient societies of the oldest civilizations wherein opium extracts, alcohol, coca leaves and other plant products were used. Even regional anesthesia in the form of compression on the nerve trunks, application of cold or use of crude local anesthetics was done in
McNarry and Goldhill compared ACDU Scale (Alert, Confused, Drowsy, Unresponsive) and AVPU scale (Alert, responds to Voice, responds to Pain, Unresponsive) by the American college of surgeons with GCS scale for neurological assessment of critically ill ward patients. Just like GCS the ACDS Scale is a method to assess the neurological status and level of
Introduction to Sevoflurane Sevoflurane is a volatile inhalational anesthetic agent that has gained significant acceptance in modern medical practice, especially for its application in both adult and pediatric anesthesia. As a halogenated ether, its chemical structure features a combination of fluoroalkyl and ether groups, which contributes to its unique properties. Its molecular formula is C4H03F7,
Malignant hyperthermia (MH) is a hypermetabolic disorder of skeletal muscle that is triggered in susceptible individuals by several inhalation anesthetic agents (sevoflurane, desflurane, isoflurane, halothane, enflurane, and methoxyflurane) and succinylcholine. These anesthetic triggers cause intracellular hypercalcemia in skeletal muscle by decreasing the uptake of calcium by the sarcoplasmic reticulum. The intracellular hypercalcemia activates metabolic pathways
Ether is still very rarely used in many Developing countries like India. First public demonstration of ether was given by W.T.G. Morton on I6th October 1846 for the removal of jaw tumor. Physical Properties of Ether : • It is pungent smelling liquid decomposes in presence of light, air and heat so stored in amber
Lesions requiring Cranial Base Surgery represent a heterogeneous group of lesions and vascular malformations associated with cranial base bony structures. These pathologies provide a challenging situation for both neurosurgeon and neuroanaesthesiologist. There is abundance of structures especially vital centers in a relatively smaller infratentorial space. Many patients present with signs and symptoms of brain stem
An important part of rapid sequence induction is Cricoid pressure was first described by Sellick in 1961, hence it is called as sellicks manoeuvre. The Cricoid pressure is used for the compession of the upper esophagus to close the aspiration of gastric contents during rapid sequence intubation. Pulmonary aspiration of gastric contents occurs usually in
The effect of Halothane on the liver is that it causes hepatitis called as halothane hepatitis. Incidence of massive hepatic necrosis as a result of halothane hepatitis is 1 in 35,000. Risk factors for halothane hepatitis are: Multiple exposures is single most important factor. Hypoxia. Middle age. Obesity. Females. Patient with other autoimmune diseases. Pathologic
General Anesthesia mask is used to ventilate the patient without intubation or before intubation. The mask significantly increases amount of dead space. These are available in sizes from 0 to 4 numbers. Face mask should be made of antistatic rubber. At the bottom of General Anesthesia mask there is air filled cuff which has soft cushioning effect.
