Drugs

Beta blockade

Beta blockade prior to instituting other vasodilator drugs in aortic dessection management is essential. The following case presentation demonstates the importance of beta blockade in Aortic dissection management. A 44-year-old man whose only past medical history consists of hypertension and unilateral cataracts presents to his local emergency department with the acute onset of severe tearing […]

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Hypoxia Effects

Physiological response to hypoxia is commonly seen. It depends upon speed and severity of the oxygen lack. The response may be direct or indirect. The direct Hypoxia effects are on cardiorespiratory systems and the secondary effects are due to the failure of organs like brain, liver, kidney and heart. The Hypoxia effects on these organs

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Diazepam uses

Diazepam remains a popular oral drug for preoperative medication of adults and is the benzodiazepine most likely to be selected for management of delirium tremens and treatment of local anesthetic induced seizures. This is considered to be one of the diazepam uses that are very common. Production of skeletal muscle relaxation by diazepam is often

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Propofol Anesthesia

Propofol anesthesia has become the induction drug of choice for most of the surgical procedures, especially when rapid and complete awakening is desirable. Continuous IV infusion of Propofol anesthesia with or without other anesthetic drugs, is commonly used in TIVA and for sedation. Due to its quick onset and offset characteristics it is also becoming

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Propofol pharmacokinetics

Despite the rapid clearance of propofol pharmacokinetics by metabolism, there is no evidence of impaired elimination in patients with cirrhosis of the liver. Chronic alcoholism does not change the propofol pharmacokinetics significantly. Extrahepatic elimination of propofol occurs during the anhepatic phase of orthotopic liver transplantation. Renal dysfunction does not influence the clearance of propofol. Patients

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Opoid crisis

The action of Opoid crisis on hypothalamic nuclei also may be involved in producing slight fall in the body temperature. Modulation of pain through diencephalic areas like periaqueductal grey, thalamic center and hypothalamic areas is produced. The mid-brain (Mesencephalon) basal nuclei, especially due to excitation of parasympathetic region of Edinger Westphal nucleus of the oculomotor nerve

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Common benzodiazepines

Among the common benzodiazepines that are used in anesthesia today are three: namely diazepam, midazolam and lorazepam. Benzodiazepines produce varying degree of anxiolysis, sedation, anticonvulsant actions and anterograde amnesia. Benzodiazepines also produce some degree of skeletal muscle relaxation but that is not sufficient for surgical procedures; and they also do not decrease the dose requirements

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