Anesthesia General

Propofol General Anesthesia

Propofol is a global central nervous system depressant. Propofol general anesthesia decreases cerebral metabolic rate for oxygen (CMRO2), cerebral blood flow (CBF), and intracranial pressure (ICP). Decrease in CBF is more than sevoflurane. Propofol is a cerebral vasoconstrictor and thus lowers ICP. Propofol decreases ICP greater than isoflurane and sevoflurane while cerebral perfusion pressure is […]

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Halogenated volatile agents

Halogenated volatile agents are inhalational anesthesia gases used during surgeries to provide general anesthesia. They are metabolized to varying degrees. There is biotransformation in the liver resulting in cleavage and dehalogenation by the specific enzyme P450, which is a haemocytochrome present in the hepatic cell. Desflurane (CHF2-O-CHFCHF3): It is one of the halogenated volatile agents

Drugs

Propofol General Anesthesia

Halogenated volatile agents