Midazolam effects
Midazolam effects cerebral metabolic oxygen requirement (CMRO2) by decreasing it and cerebral blood flow, analogous to barbiturates and propofol. It causes dose-related changes in regional cerebral blood flow in brain regions associated with the normal functioning of arousal, attention, and memory. Patients with decreased intracranial compliance show little or no change in intra-cranial pressure when […]