Midazolam sedation is a useful intravenous adjunct to local or regional anesthesia for a variety of therapeutic and diagnostic procedures. Midazolam sedation in doses of 1.0 to 2.5 mg IV (onset within 30-60 sec, time to peak affect 3 to 5 minutes, duration of sedation 15 to 80 minutes) is effective for sedation. Titrated intravenous […]
The manifestations of midazolam overdose are sedation, somnolence, confusion, impaired coordination, diminished reflexes, and untoward effects on vital signs, coma and possible cardio respiratory arrest. Treatment of midazolam overdose is the same as that followed for overdosage with other benzodiazepines. Continuous monitoring of vital signs including ECG should be immediately instituted and general supportive measures
Reiki therapy techniques have been in practice since 2nd—3rd century; it was forgotten and about 130 years back was reinvented by Dr. Mikao Usui. WHO has defined it as “Non physical healing energy comprising universal life force energy (divine in nature) having its own intelligence”. Rei: means in Japanese, universal; Ki : life force energy
Barbiturates list is explained in detail in this article. Thiopentone is prepared commercially from highly alkaline solutions as sodium salt that is readily soluble in water or saline. It is supplied as a yellowish, hygroscopic powder. The pH of a 2.5% solution of thiopental is 10.5. The following is a list of Barbiturates in common
Lorazepam drip or Ativan drip is a frequently used sedative in the intensive care unit (ICU). It is a benzodiazepine that can be administered enterally, as intermittent parenteral doses, or as a continuous infusion. The beneficial effects of lorazepam drip include anterograde amnesia and an opioid-sparing effect via a moderation of the anticipatory pain response.
Among the common benzodiazepines that are used in anesthesia today are three: namely diazepam, midazolam and lorazepam. Benzodiazepines produce varying degree of anxiolysis, sedation, anticonvulsant actions and anterograde amnesia. Benzodiazepines also produce some degree of skeletal muscle relaxation but that is not sufficient for surgical procedures; and they also do not decrease the dose requirements
Neo-Synephrine is the trade name for phenylephrine. It is a pure alpha receptor agonist and has both venous and arterial constrictive effects. Because Alpha1 receptors have been discovered in the myocardium, it is also possible that it has positive inotropic effects. In our current culture of patient safety, it is important to avoid commonly used medical
Pain control is an important aspect of critical care medicine and the use of opiate medications has typically been an important method of achieving control in the intensive care unit (ICU) setting. The brain has four opiate receptors that include the mu, kappa, delta, and sigma receptors. Currently used opioid analgesics bind to the mu
Partial agonist buprenorphine is an opioid, which strikingly differs chemically from other opioids, in that it is not related to morphine, but to another alkaloid called thebaine. So buprenorphine is a semi synthetic opioid. Pharmacodynamically, partial agonist buprenorphine is highly potent. 0.3 mg is equianalgesic with 10 mg of morphine. It has a 50 times
Pre anesthesia drugs and medicines is the term applied to the use of drugs prior to the administration of an anesthetic agent, with the objective of making anesthesia safer and more agreeable to the patient. The reasons for using pre anesthesia drugs are: For sedation, to reduce anxiety and apprehension without producing much drowsiness. To obtain an
