Incidences of anaphylaxis have been reported after induction with thiopental. The incidence of barbiturate allergy is estimated to be 1 per 30,000 patients. The majority of the patients who suffer from anaphylaxis due to barbiturate allergy also possess history of chronic allergy. Barbiturate Allergic reactions include urticaria, angioneurotic edema, other skin reactions, agranulocytosis and thrombocytopenic […]
Propofol exhibits dose-dependent effects on memory. Infusions of propofol amnesia for conscious sedation produce concentrations below those required for consistent amnesia. In the study by Matsuki et al. Propofol and midazolam did not differ in amnesic effects to non-invasive stimuli. However, for invasive stimuli, midazolam showed a stronger amnesic effect at the moderate sedation level,
There are several oxygen physical properties : 1. Oxygen is colorless, odorless and tasteless gas. 2. Specific gravity is 1.106. 3. Molecular weight is 32. 4. In normal atmospheric pressure it liquefies at 183°C. 5. Solubility in water is 2.4 volume% at 37°C and 4.9 volume% at 0°C. 6. Inflammibility—it cannot be ignited but its
There are several uses of barbiturates . Thiopental sodium is used as (1) the sole anesthetic agent for brief (15 minute) procedures, (2) for induction of anesthesia prior to administration of other anesthetic agents, (3) to supplement regional anesthesia, (4) to provide hypnosis during balanced anesthesia with other agents for analgesia or muscle relaxation, (5)
The Etomidate brand name in common use is Amidate. Amidate is a carboxylated imidazole compound. The imidazole nucleus renders etomidate, like midazolam, water soluble at an acidic pH and lipid soluble at physiologic pH. It is a non-barbiturate hypnotic without analgesic properties that has less cardiovascular and respiratory depressant actions than sodium thiopental. This lipophilic
Etomidate induces loss of consciousness rapidly (5—15 seconds) and recovery occurs in 5 to 15 minutes. The elimination Etomidate half life is 4.6 +1- 2.6 hours and total apparent volume of distribution, 4.5 +/- 2.2 L/kg. The volume of distribution of etomidate half life is large, suggesting considerable tissue uptake. The plasma clearance is 879
The sedative midazolam side effects and fluctuations in vital signs were the most frequent findings following parenteral administration of midazolam injection. These are affected by the lightening or deepening of anesthesia, instrumentation, intubation and use of concomitant drugs. The more frequently encountered fluctuations in vital signs of midazolam side effects included decreased tidal volume and/or
A special mention must be made here about the novel ways of using neuraxial regional anesthesia anticoagulation . The use started in 1979. Gradually they have become very popular and almost all the clinically available opioids have been tried by this route. Nowadays the flexibility of neuraxial regional anesthesia anticoagulation is available to be given
Etomidate sedation infusion can be used as a suitable alternative for neuroanesthesia when nitrous oxide is contraindicated. Etomidate sedation (100 micrograms/kg/ minute) has been used as a part of total intravenous anesthetic technique with a mean recovery time of about 10 minutes. The infusion is associated with minimal incidences of side effects such as thrombophiebitis
The discussion about chronic pain management anesthesiology is incomplete until and unless the very important aspect of pain is taken into wider consideration which is the chronic pain. Chronic pain is the major symptom of the majority of the patients presenting at outpatient clinics. It is the most commonly overlooked, misunderstood or wrongly labeled and
