For Sevoflurane induction , the low blood/gas solubility and lack of pungency and irritant effects make it suitable for smooth inhalational induction of general anesthesia especially in children. Loss of consciousness occurs within 1 minute after a single breath induction. Breath holding, laryngospasm and arterial desaturation are uncommon. There is haemodynamic stability in case of […]
Chronic pain is a persistent condition that affects millions of people worldwide. It can be debilitating and significantly impact a person’s quality of life. Fortunately, there are various strategies and approaches available to help manage chronic pain effectively. In this article, we will explore some of the commonly used chronic pain management strategies. 1. Medication:
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The physiologic changes in pregnancy occur in response to fetal development and eventual delivery. It is incumbent on the intensive care physician to have an understanding of the normal variants that occur in pregnancy to correctly interpret diagnostic tests and effectively treat clinical conditions. Some changes that occur in pregnancy include the following. Endocrine changes
Hepatotoxicily has been seen since the introduction of anesthetics. Chloroform and trichloroethylene have been abandoned for toxicity of inhalational anesthesia . The toxicity may be intrinsic as seen with Chloroform or acetaminophen. Halothane exhibits an allergic or hypersensitivity reaction to a drug metabolite protein. The toxicity of inhalational anesthesia with the incidence of liver injury is Halothane> Isoflurane
Doxapram injection Doxapram is a specific respiratory stimulant. It stimulates the respiratory center preferentially and has relatively less effect on cortical and spinal sites. Following intravenous doxapram injection the drug stimulates ventilation and increases cardiac output and work. Doxapram dose It is given in a dose of 1-1.5 mg/kg by intravenous injection. Intravenous infusion can also
An important part of rapid sequence induction is Cricoid pressure was first described by Sellick in 1961, hence it is called as sellicks manoeuvre. The Cricoid pressure is used for the compession of the upper esophagus to close the aspiration of gastric contents during rapid sequence intubation. Pulmonary aspiration of gastric contents occurs usually in
Trichloroethylene Trichloroethylene is also called as Trilene. It is an inhalational anesthetic gas, which was widely used until recently. It is still used in some developing countries because of its cheap cost compared to the other halogenated inhalational anesthetics. Trichloroethylene Physical Properties • It is colorless liquid. • Odor is sweet. • Mildly irritant. •
Charle’s Law: A Fundamental Gas Law What is Charle’s Law? Charle’s Law is a fundamental principle in thermodynamics that describes how gases behave under varying conditions of temperature and volume. Formulated by Jacques Charles in the late 18th century, this law states that the volume of a gas is directly proportional to its absolute temperature,
Chloroform anesthesia is prepared from chloroform chemical formula and is a potent, pleasant, non-irritant anaesthetic agent, very popular in the early days of anaesthesia. Physical properties of Chloroform chemical formula are that, it is colourless, sweet odour, non flammable, bp 6 1°C, VP 80mm Hg, blood/gas coefficient 10.3, oil/gas 394, MAC 0.62, metabolism 50% to
When it comes to total knee replacement surgery, managing pain and providing effective analgesia is of utmost importance. The procedure itself can be quite invasive and painful, and it is crucial to ensure that patients are comfortable and experience minimal discomfort throughout their recovery process. In this article, we will explore the various options available
