Drugs

Opoid crisis

The action of Opoid crisis on hypothalamic nuclei also may be involved in producing slight fall in the body temperature. Modulation of pain through diencephalic areas like periaqueductal grey, thalamic center and hypothalamic areas is produced. The mid-brain (Mesencephalon) basal nuclei, especially due to excitation of parasympathetic region of Edinger Westphal nucleus of the oculomotor nerve […]

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Propofol emulsion

Propofol is an insoluble drug that requires a lipid vehicle for emulsification. The standard propofol emulsion formulation contains 10% soya oil as the oil phase and egg lecithin as the emulsifying agent that is composed of long-chain triglycerides. This formulation supports bacterial growth new formulations contain preservatives with bactericidal action, such as propofol with EDTA

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Midazolam infusion

Midazolam infusion can be used either alone or combined with a narcotic immediately before the procedure, with supplemental doses to maintain the desired level of sedation throughout the procedure. For short endoscopic or short diagnostic procedures and direct current cardioversion, midazolam infusion of 1 mg/mL formulation is recommended for IV sedation to facilitate slow injection.

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Lorazepam uses

One of the lorazepam uses , is that the Lorazepam undergoes reliable absorption after oral and I.M. injection. After oral administration, maximal plasma concentrations of lorazepam occur in 2 to 4 hours and persist at therapeutic levels for up to 24 to 48 hours. The recommended oral dose of lorazepam uses preoperative medication which is

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Midazolam sedation

Midazolam sedation is a useful intravenous adjunct to local or regional anesthesia for a variety of therapeutic and diagnostic procedures. Midazolam sedation in doses of 1.0 to 2.5 mg IV (onset within 30-60 sec, time to peak affect 3 to 5 minutes, duration of sedation 15 to 80 minutes) is effective for sedation. Titrated intravenous

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Neo-Synephrine

Neo-Synephrine is the trade name for phenylephrine. It is a pure alpha receptor agonist and has both venous and arterial constrictive effects. Because Alpha1 receptors have been discovered in the myocardium, it is also possible that it has positive inotropic effects. In our current culture of patient safety, it is important to avoid commonly used medical

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Etomidate Half Life

Etomidate induces loss of consciousness rapidly (5—15 seconds) and recovery occurs in 5 to 15 minutes. The elimination Etomidate half life is 4.6 +1- 2.6 hours and total apparent volume of distribution, 4.5 +/- 2.2 L/kg. The volume of distribution of etomidate half life is large, suggesting considerable tissue uptake. The plasma clearance is 879

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