Critical Care

Brain Hypothermia

The capacity of deliberate Brain Hypothermia to protect the brain and other vital organs during periods of decreased oxygen delivery is used during cardiac surgery. The beneficial effects of Brain Hypothermia were empirically attributed to its ability to decrease cellular metabolism and thus delay the processes leading to irreversible cell death. Based on this, it

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Heliox

Heliox is a mixture of Helium and oxygen being considered for use in asthma patients. Therapeutic strategies for patients with pulmonary medicine often employ bronchodilators or corticosteroids to reduce airway resistance and improve airflow. As an alternative strategy, viscosity and density of the atmosphere manipulated to the same desired effect. Air consists of 21% oxygen, with

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Cyanide Toxicity with sodium nitroprusside

Cyanide Toxicity can occur with sodium nitroprusside. Hypertension is commonly seen in the perioperative setting as well as the intensive care unit (ICU). There are many agents to lower blood pressure with different mechanisms of action. One of the most potent vasodilators is sodium nitroprusside, which causes arteriolar and venous smooth muscle relaxation via nitric oxide-mediated

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Cerebral protection

Cerebral ischaemia or hypoxia may occur as a consequence of shock, vascular stenosis or occlusion, vasospasm, neurotrauma and cardiac arrest. Strategies to protect the brain i.e Cerebral protection from ischemic/hypoxic insults are based on the understanding of pathophysiological processes that follow ischemia/hypoxia to result in neuronal death. Neurologic morbidity is common in those patients experiencing

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Cardiac Output is not Left Ventricular Ejection Fraction

A common mistake made by many clinicians is that they confuse cardiac output for Left Ventricular Ejection Fraction. Lets see how Cardiac Output is not Left Ventricular Ejection Fraction . Cardiac output equals the volume of blood pumped by the heart per minute, whereas stroke volume (SV) is the amount pumped on a single beat. Cardiac output

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Hyperbaric Oxygen

Hyperbaric Oxygen means delivering the oxygen above atmospheric pressure which is 760 mmHg (or 1 atm). Special hyperbaric chambers are made for providing hyperbaric Oxygen, which are very expensive. Hyperbaric Oxygen Uses A. Poisonings: Carbon monoxide poisoning (half life of CO at 1 atm is 214 minutes which can be reduced to 19 minutes at

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