Oxygen Toxicity occurs when excessive oxygen inhalation is done as in prolonged ventilation with hundred percent (100%) oxygen. When the inspired oxygen saturation or FiO2 of a patient on oxygen therapy is kept for long time Toxicity of oxygen is bound can take place. FiO2 of 100 % should not be kept for more than 12 […]
Autologous blood Transfusion Techniques: AutoIogous Blood The blood of a person himself is called as autologous blood. Usually, 3 to 4 units of patient’s own blood are taken 4 to 6 weeks before surgery but hematocrit should not be allowed to fall below 35% and hemoglobin less than 11 g%. The patient’s blood is transfused back
Many drugs are metabolized to active metabolites. This is usually carried out by the liver in the form of reductions, oxidations, and the addition of methyl, acetyl, and other groups. watchesbest.org While metabolites are usually a fraction as potent as the parent compound, in some situations they may be more potent and may accumulate to
Clinical Causes of Hypoxia During Anesthesia Every doctor should know the answer to the basic question What causes Hypoxia . Factors responsible: 1. Preanaesthesia factors • Poor physiological status • Drug intake • Premedication with narcotics and sedatives depress the respiration • Decreased compensatory mechanism due to any cause 2. Decreased partial pressure and concentration of the inspired oxygen in
Little substantial human data exists concerning the impact of fluids on the brain, which may guide rational IV Fluid Replacement in neurosurgical patients. Therefore, recommendations arise from known factors that influence water movement into the brain. IV Fluid Replacement in neurosurgical patients can alter three properties of the blood, viz., osmolality, colloid oncotic pressure and
What are the Indications for and Contraindications to Thrombolytics? Mr. XXX is a 66-year-old male who is postoperative day number one after hip replacement surgery and complains of acute onset of chest pain and shortness of breath. An electrocardiogram (ECG) is performed that shows new ST-segment elevation in leads II, III, and aVF. You are alone
Indications for and Contraindications to Thrombolytics Read More »
Chronic oxygen deficiency is defined as a prolonged lack of oxygen to the body as that occurs in living in high altitudes or by having severe chronic lung disease. Chronic oxygen deficiency have the following effects : There is decreased mental efficiency due the prolonged deficiency of oxygen Sleepiness, headache, lassitude and fatigubility are also common Euphoria is also
Virtually all burn patients have elevated core body temperatures and even a leukocytosis. Thus, fever after burn patients is not a reliable indicator of infection. One study in children found that fever had no predictive value for the presence of infection and physical examination was a more reliable source of information about wound infection and
Cerebral ischaemia or hypoxia may occur as a consequence of shock, vascular stenosis or occlusion, vasospasm, neurotrauma and cardiac arrest. Strategies to protect the brain i.e Cerebral protection from ischemic/hypoxic insults are based on the understanding of pathophysiological processes that follow ischemia/hypoxia to result in neuronal death. Neurologic morbidity is common in those patients experiencing
Ketamine receptors have GABAA receptor agonistic properties. Subanaesthetic doses of Ketamine receptors inhibits tonic convulsions induced by the GABAA receptor antagonist bicuculline. The GABAA receptor agonist, muscimol, potentiates ketamin induced anesthesia whereas, bicuculline antagonizes it. Opioid Receptors : Ketamine receptors has been reported to interact with opioid receptors in clinically relevant concentration. Other studies have suggested
