Many drugs are metabolized to active metabolites. This is usually carried out by the liver in the form of reductions, oxidations, and the addition of methyl, acetyl, and other groups. watchesbest.org While metabolites are usually a fraction as potent as the parent compound, in some situations they may be more potent and may accumulate to
There are numerous uses of carbon dioxide in modern anesthesia. It is used : • To increase depth of anesthesia with volatile anesthetic agents by stimulating respiration.- • To increase cerebral blood flow during carotid artery surgery. • To produce hyperventilation during blind nasal intubation. • To stimulate the respiration after artificial hyperventilation. • It
AMBU Ventilation is an important part in resuscitation of an apnoeic person or a person who is not breathing. The AMBU of an AMBU bag is an abbreviation for ‘Artificial Manual Breathing Unit’. The AMBU bag is used to ventilate the patient. An AMBU Ventilation unit consists of one self inflating bag made up of
Clinical Causes of Hypoxia During Anesthesia Every doctor should know the answer to the basic question What causes Hypoxia . Factors responsible: 1. Preanaesthesia factors • Poor physiological status • Drug intake • Premedication with narcotics and sedatives depress the respiration • Decreased compensatory mechanism due to any cause 2. Decreased partial pressure and concentration of the inspired oxygen in
Chest pain in the intensive care unit (ICU) is a common and potentially serious complaint. The differential diagnosis of noncardiac chest pain is broad, and the physician must not be limited to cardiac etiologies, although myocardial infarction and angina must always be considered. The initial approach to Noncardiac Chest Pain requires a rapid evaluation, history,
Percutaneous coronary intervention or pci cardiac with stenting has revolutionized the care for patients with acute myocardial infarctions. Intracoronary stent placement in pci cardiac reduces the long-termrecurrence of stenosis. In addition, the combination of stenting with administration of glycoprotein IIb/IIIa (GP IIb/IIIa) inhibitor agents, which prohibit the binding of fibrinogen and proteins to platelets, has
Nitrogen is present in the atmosphere and it constitutes 78.08% of total air. Moreover, the use of nitrogen is growing very rapidly these days. Use of nitrogen in medicine is helpful as it can be used as diluent of oxygen in order to avoid oxygen toxicity. It is stored in either compressed air or in
Despite the great strides made over the last decades in improving survival after thermal injury, infectious complications remain an important cause of morbidity and mortality. Nearly 50% of all burn deaths are related to infected burn. Several factors contribute to the high incidence and severity of infection in burn patients. First, a profound immune suppression
Autologous blood Transfusion Techniques: AutoIogous Blood The blood of a person himself is called as autologous blood. Usually, 3 to 4 units of patient’s own blood are taken 4 to 6 weeks before surgery but hematocrit should not be allowed to fall below 35% and hemoglobin less than 11 g%. The patient’s blood is transfused back
Missed injuries, commonly referred to as the trauma surgeon’s nemesis, are an expected occurrence in the management of multiply injured patients. The definition of a missed injury is institution specific. Generally speaking, however, a missed injury is an injury identified at some defined time after the initial assessment. Missed injuries are not frequently life-threatening. However,
