Ketamine is associated with psychedelic effects and dependence. Well the question here arises is that Is Ketamine addictive ?
These effects are dose-related and comprised of multimodal hallucinatory experiences, a sense of slowing, paranoid ideation and enhancement of sexual, musical and sensory enjoyment.
The mechanisms of these phenomena are largely due to its complex multi-receptors actions, notably through the excitatory amino acids through mainly the NMDA receptors.
Hence, dependence and addiction, although uncommon with ketamine than other sedatives like benzodiazepines or opioids, still occurs.
This ketamine addiction is not that serious and its significance is nowhere comparable to the dependence seen with morphine and other opioids.