Analeptic Drugs are Cenrtral nervous system stimulants or CNS stimulants that stimulate respiration and also the brain. The different Analeptic Drugs are: Bemegride Nikethamide Doxapram These drugs help to restore the drug-induced depressed function towards normal. Ideally there should be pharmacological antagonism and the analeptic drug should block the depressant drug activity either by inactivation or […]
Doxapram injection Doxapram is a specific respiratory stimulant. It stimulates the respiratory center preferentially and has relatively less effect on cortical and spinal sites. Following intravenous doxapram injection the drug stimulates ventilation and increases cardiac output and work. Doxapram dose It is given in a dose of 1-1.5 mg/kg by intravenous injection. Intravenous infusion can also
What is Morphine sulphate Morphine sulphate injection is an opium alkaloid and a standard potent opioid analgesic. This opioid acts as an anxiolytic, hypnotic and sedative. It causes both the stimulation and the depression of the central nervous system. The depression caused by morphine leads to analgesia, respiratory depression, depression of cough reflex and sleep
Fentanyl citrate injection is a potent narcotic analgesic and an opioid. It is said to be 100 times more potent than morphine and 1000 times more potent than pethidine. Fentanyl citrate injection effects It causes profound analgesia and sedation in a dose of 0.1 mg intramuscular. Like other narcotic analgesics it causes respiratory depression and is
Pethidine injection is a synthetic morphine like analgesic. this opioid medication has about one tenth as powerful compared to morphine. This drug has sedative and tranquilizing effects also. It may cause euphoria and sleepiness. Unlike morphine it tends to relax smooth muscles and thus relieves most types of pain associated with plain muscle spasm. But
Phenoperidine a new opoid Phenoperidine is chemically related to pethidine and is similar to fentanyl. It is one of the new opioids available now for use in anesthesia for analgesia and as a pre anesthesia medication. Phenoperidine potency One milligram of this new opioid drug is equianalgesic to 100 mg pethidine. Phenoperidine Onset and Duration of
What is Buprenorphine injection? Is it an opiod? Buprenorphine is derived from the opium alkaloid thebaine and is closely related to morphine. It has powerful opiod agonist actions as well as partial opiod antagonist actions. It does not seem to cause addiction and physical dependence. Buprenorphine injection Potency It is a potent analgesic, 0.4 mg is equipotent
Pentazocine injection is a synthetic narcotic analgesic derived from benzomorphan. Pentazocine Potency Its analgesic potency of 30 mg is said to be equal to 10 mg of morphine or 75 to 100 mg of pethidine. Pentazocine Dose The usual dose in adults is 20 to 60 mg i.m. (about 1 mg/kg). The oral dose ranges from
Acute barbiturate poisoning causes depression of the CNS, particularly the respiratory system causing decreased breathing, and the cardiovascular system causing a peripheral circulatory collapse. The frequent and often fatal complications are respiratory (atelectasis, pulmonary edema and bronchopneumonia) or renal (acute renal shutdown). Treatment of acute barbiturate poisoning The severity of barbiturate poisoning is assessed by
What is Nitrous oxide gas ? Nitrous oxide gas is a Gaseous Anesthetic agent. Nitrous oxide gas is a colorless, inorganic gas with a sweet taste. The oxygen in the nitrous oxide molecule is not available for tissue respiration as nitrous oxide does not undergo significant decomposition in the body. Nitrous oxide gas, if administered
