Versed side effects

The versed side effects related to Respiratory are respiratory arrest, respiratory failure, apnoea, hypoxia, oxygen desaturation.

Danger of respiratory disorders may increase when midazolam is administered with opioids. Therefore, the dosage of both agents should be reduced.

Limited information is available from published literature regarding the use of midazolam in paediatric patients.

However, based on information obtained from published literature and spontaneous versed side effects reporting, the safety profile in children more than 1 month of age appears to be very similar to that observed in adults.

The most frequent acute events were airway compromise and hypoventilation. This most often occurred when used in conjunction with opiates or other anaesthetic agents. One of the most common versed side effects with long-term use was withdrawal syndrome.

Psychiatric: withdrawal syndrome, combative reaction, agitation, hallucination.

Central and peripheral nervous system: convulsions, excessive sedation, tonic/clonic convulsions, cerebral convulsion, and lethargy. Convulsions occurred primarily in neonates (under 4 months old) and/or children with history of seizures.

Cardiovascular: hypotension, bradycardia, cardiac/cardiopulmonary arrest.

Miscellaneous: lack of efficacy, paradoxical response, and therapeutic response decreased.

Dermatological: rash, urticaria, erythema, hives, skin necrosis and wheals.

Laboratory Abnormalities –

Isolated elevations in certain parameters of liver function like AST, ALT, alkaline phosphatase and total bilirubin, as well as isolated changes in total protein and albumin, have been reported under versed side effects .


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