Phenoperidine new opiod

Phenoperidine a new opoid

Phenoperidine is chemically related to pethidine and is similar to fentanyl. It is one of the new opioids available now for use in anesthesia for analgesia and as a pre anesthesia medication.

Phenoperidine potency

One milligram of this new opioid drug is equianalgesic to 100 mg pethidine.

Phenoperidine Onset and Duration of action

The onset of action is usually rapid within 2 to 3 min and the duration of action ranges from 1 to 2 h.

Phenoperidine Effects

The drug causes profound depression of respiration in common with all opioid agents. It has little effect on cardiovascular system in clinical doses.

It is used for supplementation of anesthesia in doses of 1 to 3 mg. It is also used with droperidol in neuroleptanalgesia. this medication can also be given orally and i.m.

Phenoperidine metabolism and excretion

The drug is mostly excreted by the kidneys and the rest is broken down in the liver to pethidine and pethidinic acid, most of which is excreted in urine.

It can be used as a pain killer in surgeries or after surgeries like other opioids like morphine or fentanyl.

But is not commonly used in clinical practice. One of the reasons is that it is not widely available. Also the cost of this new opioid drug is high compared to other easy available alternatives.

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