Category: Drugs

Etomidate Drug Interactions

Etomidate shortens the onset time of neuromuscular block with vecuronium. This etomidate drug interactions enhances the bradycardia induced by vecuronium. Miller’s anesthesia says the following about etomidate drug interactions – …

Etomidate Metabolism

Etomidate metabolism is rapidly metabolized by hydrolysis of the ethyl ester side chain to its carboxylic acid ester, resulting in a water-soluble, pharmacologically inactive compound. Hepatic microsomal enzymes and …

Oral Transmucosal Etomidate

Oral transmucosal etomidate produces dose-related increases in sedation and clinically significant serum concentrations.  Animal studies documented etomidate as highly permeable through the buccal mucosa with rapid onset and offset …

Ketamine Effects

Some of the Ketamine effects discussed here. Ketamine does not increase the intraocular pressure (lOP) in routine analgesic doses. Even after the IM injection of 8 mg/kg, ketamine doses …

Benzodiazepines dependance

Benzodiazepines dependance may produce physical and psychological dependence after chronic (>6 months) use of commonly prescribed low-potency benzodiazepines. Withdrawal symptoms (irritability, insomnia, tremulousness) appear within 1 to 2 days …

Midazolam IM

For sedation prior to anaesthesia or procedures, for longer and/or more stimulating procedures, midazolam IM can be used to facilitate insertion of an IV catheter for titration of additional …

Midazolam IV

Midazolam IV is the first benzodiazepine that was produced primarily for use in anaesthesia. Walser and colleagues in 1976 “first described midazolam, the first clinically used water-soluble benzodiazepine. The …

Midazolam syrup

As a group, paediatric patients generally require higher doses of midazolam than do adults and younger children may require higher doses than older children. In obese individuals, the midazolam …

Midazolam administration

Reactions such as agitation, involuntary movements, hyperactivity and combativeness are usually reported during midazolam administration . Should such reactions occur, the response to each dose of midazolam and all …

Midazolam oral dose

Midazolam oral is the most commonly used oral preoperative medication for children. A syrup is effective for producing sedation and anxiolysis at a Midazolam oral dose of 0.25 mg/kg with …