Category: Drugs

Oxygenation Capacity

Oxygenation capacity is the volume of oxygen at standard pressure and temperature carried by 100 mL of blood after saturation with room air. Oxygenation capacity includes the oxygen in …

Benzodiazepine equivalence

Among benzodiazepine equivalence , differences in the onset and duration of action are due to their potency, lipid solubility and pharmacokinetics. Benzodiazepine equivalence is used to understand the relative …

Hypoxia Mechanism

Hypoxia mechanism Following phases are included in the Hypoxia mechanism : 1. Anoxic hypoxia—Gas phase. There is inadequate supply of oxygen to the lungs, or the lung is not …

Phenobarbital Status Epilepticus

Phenobarbital status epilepticus that does not respond to first-line ben-zodiazepines (lorazepam or diazepam) or to second-line antiepileptic drugs (phenytoin/fosphenytoin, phenobarbital or valproate) is usually considered refractory and requires more …

Barbiturate Allergy

Incidences of anaphylaxis have been reported after induction with thiopental. The incidence of barbiturate allergy is estimated to be 1 per 30,000 patients. The majority of the patients who …

Propofol Myoclonus

Excitatory events following propofol administration are well described. The pathophysiology of these propofol myoclonus movements is not known. The drug should be used cautiously in patients with movement disorders. …